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Sen‐Wen Teng Hsin‐Yu Sung Yu‐Chieh Wen Ssu‐Yu Chen Ronald Lovel Wen‐Ying Chang Tang Bo‐Chung Wu Yogi Cheng‐Yo Hsuan Willie Lin Abstract Mesenchymal stem cells (MSCs) play an important role as immune modulator through interaction with several immune cells, including macrophages. In this study, the immunomodulatory potency of human umbilical cord‐derived mesenchymal stem cells (hUC‐MSCs) was demonstrated in the in vivo middle cerebral artery …

Potential surrogate quantitative immunomodulatory potency assay for monitoring human umbilical cord‐derived mesenchymal stem cells production Read More »

Sang Eun Lee,1 Seung-Ju Lee,1 Song-Ee Kim,1 Kinam Kim,2 Boyoung Cho,2 Kyounghwan Roh,3 and Soo-Chan Kim4 Published January 25, 2021 – More info Abstract BACKGROUND. Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable disease that causes severe mucocutaneous fragility due to mutations in COL7A1 (encoding type VII collagen [C7]). In this phase I/IIa trial, we evaluated the safety and possible clinical efficacy of intravenous infusion of …

Intravenous allogeneic umbilical cord blood–derived mesenchymal stem cell therapy in recessive dystrophic epidermolysis bullosa patients Read More »